Multiple Tablet Strengths Optimizer

Match a target dose (mg) using available tablet strengths while reducing tablet burden

Calculator

Optimize a combination of strengths to hit a target dose

Target dose (mg)

Strength 1 (mg)

Strength 2 (mg)

Strength 3 (mg)

Allow going over target (shows “over by” amount). Default is under/equals only.

How it works

Enter a target dose (mg) and up to three available tablet strengths (mg per tablet). The calculator searches combinations and chooses the best match using simple rules (closest dose, then fewer tablets).

This is useful when multiple strengths exist and you want to reduce pill burden without changing the intended dose.

Method

Achieved dose (mg) = (n1 × s1) + (n2 × s2) + (n3 × s3)

Difference = Target − Achieved (remainder or “over by”)

Worked examples

Example 1: Target 750 mg; strengths 500 mg and 250 mg

1 × 500 mg + 1 × 250 mg = 750 mg (2 tablets)

Example 2: Target 1400 mg; strengths 500, 250, 100

2 × 500 mg + 1 × 250 mg + 1 × 100 mg = 1350 mg (remainder 50 mg)

If remainder is clinically significant, consider a different strength, scored fraction (if allowed), or liquid.

Frequently asked questions

Clinical reminder: Always follow local protocols and consult medication information sheets. These examples are for calculation practice only.

References & sources

Institute for Safe Medication Practices (ISMP)

Medication safety resources and error prevention guidance.

Therapeutic Goods Administration (TGA) – Product Information

Australian product information and safety updates.

British National Formulary (BNF) – NICE

Prescribing guidance, formulations, and administration notes.

How it works

This is useful when multiple strengths exist and you want to reduce pill burden without changing the intended dose.

Worked examples

Example 1: Target 750 mg; strengths 500 mg and 250 mg

1 × 500 mg + 1 × 250 mg = 750 mg (2 tablets)

Example 2: Target 1400 mg; strengths 500, 250, 100

2 × 500 mg + 1 × 250 mg + 1 × 100 mg = 1350 mg (remainder 50 mg)

If remainder is clinically significant, consider a different strength, scored fraction (if allowed), or liquid.

Frequently asked questions

Clinical reminder: Always follow local protocols and consult medication information sheets. These examples are for calculation practice only.

Multiple Tablet Strengths Optimizer

How it works

Method

Worked examples

Frequently asked questions

QIs this always “perfectly optimal”?

QShould I allow going over the target dose?

QCan I mix different formulations?

QWhat if the remainder is clinically significant?

References & sources

Multiple Tablet Strengths Optimizer

How it works

Method

Worked examples

Frequently asked questions

QIs this always “perfectly optimal”?

QShould I allow going over the target dose?

QCan I mix different formulations?

QWhat if the remainder is clinically significant?

References & sources