Katz hyperglycaemia sodium correction (1.6)
Formula originally described by Murray A. Katz.
Used for: Interpretation of serum sodium in the presence of hyperglycaemia
Historical research profile. Murray A. Katz is not affiliated with or endorsed by MedMaths.
Medicine and physiology
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Murray A. Katz, MD, was a physician and academic whose work included renal physiology, diabetes and electrolyte physiology. In 1973 he published the New England Journal of Medicine paper that described the classic estimate that serum sodium falls by about 1.6 mmol/L for each 100 mg/dL rise in glucose. Johns Hopkins alumni records later described him as a professor of medicine and physiology; he died in 2008.
Formula history
Formula originally described by Murray A. Katz.
Used for: Interpretation of serum sodium in the presence of hyperglycaemia
Evidence trail
Katz MA. Katz MA — Hyperglycemia-induced hyponatremia: calculation of expected serum sodium depression. New England Journal of Medicine. 1973;289(16):843-844
Original 1973 publication describing the classic estimate that serum sodium decreases by about 1.6 mmol/L for each 100 mg/dL rise in glucose; this is the historical source for the Katz correction used by MedMaths.
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This profile summarizes the published work and draws on the original publications above and verified external sources. It isn't a calculator or clinical advice. Murray A. Katz isn't affiliated with MedMaths and hasn't endorsed it. Anything we couldn't confirm is left blank, not estimated.
Reference data verified: 2026-08-12
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