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Clinical calculation knowledge library

MedMaths Calculation Guides

Browse plain-English Guides by the clinical problem you are trying to solve. Each Guide connects the calculation to its formula, worked method, limitations, safety boundaries and supporting references.

Practise dosage calculations by lesson
31 GuidesWorked methods & limitationsReferences & safety context

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Use a Guide when you want to understand the method. Use the calculator directory when you already know which calculation you need.

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Start with what you are trying to work out

Jump straight into the part of the Guide library that matches the task in front of you.

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3 Guides

Medication Calculations

Dose, tablet, weight-based and medication-unit calculations explained step by step.

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5 Guides

Medication Preparation

Read labels, measure volumes, reconstitute medicines and separate reconstitution from dilution.

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7 Guides

Medication Safety & Foundations

Build the habits around units, rounding, reasonableness, dose limits and safe administration.

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4 Guides

IV & Infusions

Understand gravity drip rates, volume-time-rate relationships, pump rates and weight-based infusions.

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3 Guides

Paediatrics

Compare paediatric maintenance-fluid methods and understand the daily and hourly rules.

Explore Guides
2 Guides

Renal Function

Understand Cockcroft-Gault, eGFR and why the renal estimate required by a source matters.

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4 Guides

Laboratory Calculations

Interpret anion gap, sodium correction, calcium correction and serum osmolality calculations.

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3 Guides

Body Measures & Dosing Weight

Compare BSA formulas, BSA medication dosing and ideal versus adjusted body weight.

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Featured Guides

A few useful places to start

These examples show the range of MedMaths Guides: reading medication information, understanding an IV calculation, and comparing paediatric fluid methods.

Medication labels and concentration

Calculation guide

How to Read Medication Labels and Concentrations

Learn how to identify the exact current medication product, dosage form and strength basis, separate total amount/total volume from per-mL concentration, and stop when prepared-label information is missing or unclear.

About 10 minRead Guide
IV calculations

Formula explainer

IV drip rates explained: drop factor, gtt/min and common errors

Understand what the drop factor means, why gtt/mL and gtt/min are different, how gravity flow relates to mL/hr, and where calculation errors happen.

About 7 minRead Guide
Paediatric maintenance fluids

Formula comparison

Paediatric maintenance fluids explained: 4-2-1 vs 100-50-20

100-50-20 is the Holliday-Segar daily maintenance method; 4-2-1 is a rounded hourly shortcut based on the same weight bands. This guide explains the relationship, why the totals can differ, and the clinical limits of full maintenance.

About 9 minRead Guide

Full directory

All MedMaths Guides

Every Guide is listed below by clinical area. Use the quick-jump links to move through the library.

Medication calculationsPreparationSafety & foundationsIV & infusionsPaediatricsRenal functionLaboratory calculationsBody measures

Medication Calculations

3

Dose, tablet, weight-based and medication-unit calculations explained step by step.

Medication units and concentration

Calculation guide

Medication Units and Units/mL Explained

Understand medication units, units/mL concentration, units-to-volume and hourly-rate relationships, insulin concentration/device boundaries, and common units-based errors.

About 8 minRead Guide
Weight-based medication dosing

Calculation guide

Weight-Based Medication Dosing: mg/kg to mL Explained

Learn pediatric and paediatric weight-based medication dosing from a verified mg/kg order to liquid volume, including per-dose vs per-day orders, divided doses, current kilograms, concentration and safety checks.

About 9 minRead Guide
Tablet medication calculations

Calculation guide

Tablet Dose Calculations Explained: Formula & Worked Examples

Understand D/H × Q, what Q really means, how to match units, how per-dose and daily-total orders differ, and why fractional tablet or non-whole capsule results need a separate product-specific check.

About 10 minRead Guide

Medication Preparation

5

Read labels, measure volumes, reconstitute medicines and separate reconstitution from dilution.

Medication preparation

Formula comparison

Reconstitution vs dilution: what's the difference?

Separate reconstitution from dilution, understand where final volume and concentration come from, and choose the right MedMaths calculation without mixing preparation stages.

About 8 minRead Guide
Medication syringe measurement

Calculation guide

How to Read a Medication Syringe in mL

A step-by-step guide to reading mL syringe graduations, finding the value of each small mark, matching a known mL target to the scale, and recognising when device type or syringe size matters.

About 8 minRead Guide
Medication labels and concentration

Calculation guide

How to Read Medication Labels and Concentrations

Learn how to identify the exact current medication product, dosage form and strength basis, separate total amount/total volume from per-mL concentration, and stop when prepared-label information is missing or unclear.

About 10 minRead Guide
C₁V₁ = C₂V₂ medication dilution

Formula explainer

C₁V₁ = C₂V₂ Explained for Medication Dilution

Learn how C₁V₁ = C₂V₂ works for medication dilution, what each value means, how to read dilute-to versus dilute-with wording, and where product-specific preparation rules begin.

About 12 minRead Guide
Medication reconstitution

Methodology

Medication Reconstitution Explained

Learn how to calculate from a reconstituted medication, use a stated concentration, distinguish diluent from final volume, handle solution-versus-suspension concepts, and verify product-specific preparation context.

About 12 minRead Guide

Medication Safety & Foundations

7

Build the habits around units, rounding, reasonableness, dose limits and safe administration.

Medication maths unit conversions

Calculation guide

Medication Maths Unit Conversions Explained

Learn medication math unit conversions for mass, volume and time, safe decimal and microgram notation, source-supplied kg/lb conversion, and why mg to mL or medication units need product-specific information rather than a universal conversion.

About 10 minRead Guide
Reading medication maths questions

Calculation guide

How to Read a Medication Maths Question

Learn how to decode medication maths and dosage calculation word problems using the current order, verified product, exact target, matching units and a STEP when the problem is multi-stage.

About 11 minRead Guide
Medication calculation methods

Methodology

Medication Calculation Methods Explained

Understand how the formula method, ratio and proportion, and dimensional analysis organise the same medication relationship, when each method is useful, and why correct setups should agree.

About 11 minRead Guide
Medication calculation rounding

Methodology

Rounding Medication Calculations Safely

Learn nursing dosage-calculation rounding rules, nearest tenth/hundredth language, why verified inputs and intermediate values stay unrounded, and how medication notation differs from device precision.

About 10 minRead Guide
Medication administration rights and safety checks

Methodology

Medication Administration Rights & Safety Checks

Use six core medication administration rights plus broader indication, response, barcode and high-risk safeguards, including when to stop for prescriber clarification or pharmacy formulation advice.

About 12 minRead Guide
Medication calculation checking

Methodology

How to Check a Medication Calculation Answer

Use one six-step medication-maths check: identify the target, verify active values, align units, assess scale, match supplied limits, then reverse-check the arithmetic.

About 11 minRead Guide
Safe dose ranges and maximum doses

Methodology

Safe Dose Ranges and Maximum Doses Explained

Calculate lower and upper weight-based limits, keep per-dose and per-day values separate, apply a matching-basis maximum, and compare a prescribed dose without treating arithmetic as clinical approval.

About 12 minRead Guide

IV & Infusions

4

Understand gravity drip rates, volume-time-rate relationships, pump rates and weight-based infusions.

IV calculations

Formula explainer

IV drip rates explained: drop factor, gtt/min and common errors

Understand what the drop factor means, why gtt/mL and gtt/min are different, how gravity flow relates to mL/hr, and where calculation errors happen.

About 7 minRead Guide
Weight-based infusion calculations

Calculation guide

mcg/kg/min Infusions Explained: Dose Rate and Pump Rate

Learn how mcg/kg/min connects dosing weight, time and infusion concentration to mL/hr, including forward and reverse calculations, unit checks and high-risk infusion safety boundaries.

About 10 minRead Guide
IV volume, time and rate

Calculation guide

IV Volume, Time and Rate Explained

Understand how IV volume, time and mL/hr fit together, why the same formula can solve for rate, volume or time, and how to handle minutes, remaining volume and common unit mistakes.

About 12 minRead Guide
Medication dose rate vs pump rate

Calculation guide

Medication Dose Rate vs Pump Rate Explained

Understand dose rate versus pump rate, calculate mg/hr from concentration and mL/hr, convert mg/hr and mg/min, and recalculate mL/hr after an authorised medication-rate or concentration change.

About 12 minRead Guide

Paediatrics

3

Compare paediatric maintenance-fluid methods and understand the daily and hourly rules.

Paediatric maintenance fluids

Formula comparison

Paediatric maintenance fluids explained: 4-2-1 vs 100-50-20

100-50-20 is the Holliday-Segar daily maintenance method; 4-2-1 is a rounded hourly shortcut based on the same weight bands. This guide explains the relationship, why the totals can differ, and the clinical limits of full maintenance.

About 9 minRead Guide
Paediatric maintenance fluids

Formula explainer

The 100-50-20 Rule for Paediatric Maintenance Fluids Explained

Understand what the 100-50-20 rule estimates, why the first, second and later kilograms use different daily amounts, where the Holliday-Segar method came from, and what the result does not tell you by itself.

About 10 minRead Guide
Paediatric maintenance fluids

Formula explainer

The 4-2-1 Rule for Paediatric Maintenance Fluids Explained

Understand why the 4-2-1 rule uses 4, 2 and 1 mL/kg/hr, how it relates to the daily Holliday-Segar method, how the stepped bands work, and why rounded hourly totals can differ from 100-50-20.

About 10 minRead Guide

Renal Function

2

Understand Cockcroft-Gault, eGFR and why the renal estimate required by a source matters.

Renal dosing support

Formula explainer

The Cockcroft-Gault equation explained

What the Cockcroft-Gault equation calculates, why weight-method selection matters, and when CrCl differs from eGFR.

About 9 minRead Guide
Renal dosing support

Formula explainer

eGFR vs CrCl: which renal function estimate should you use?

Understand how CKD-EPI eGFR and Cockcroft-Gault CrCl differ, why their values may not match, and how to follow the estimate and units required by the current source.

About 8 minRead Guide

Laboratory Calculations

4

Interpret anion gap, sodium correction, calcium correction and serum osmolality calculations.

Laboratory interpretation

Formula explainer

How to interpret the anion gap

Interpret the anion gap after calculation: local reference interval, albumin, GOLDMARK, DKA limitations, normal-gap acidosis and low or negative gaps.

About 9 minRead Guide
Laboratory interpretation

Formula explainer

Corrected sodium in hyperglycaemia: what the number means

Why high glucose can lower measured sodium, what a corrected sodium estimate represents, why Katz and Hillier differ, and what the number cannot tell you on its own.

About 8 minRead Guide
Laboratory interpretation

Formula comparison

Corrected calcium vs ionised calcium: what's the difference?

A plain-English comparison of total, albumin-corrected and ionised calcium, including why the results can disagree and where correction equations are limited.

About 8 minRead Guide
Serum osmolality and osmol gap interpretation

Formula explainer

Calculated Serum Osmolality and Osmol Gap Explained

Understand directly measured vs calculated serum osmolality, effective osmolality/tonicity, what the osmol gap represents, why formulas and ethanol coefficients change the result, and why the gap must be interpreted as a clue rather than a diagnosis.

About 11 minRead Guide

Body Measures & Dosing Weight

3

Compare BSA formulas, BSA medication dosing and ideal versus adjusted body weight.

Body surface area

Formula comparison

Which BSA formula should you use?

A plain-English comparison of Mosteller, Du Bois, Haycock and Gehan & George, why their estimates differ, and how to handle formula choice safely.

About 8 minRead Guide
Dosing weight

Formula comparison

Ideal vs adjusted body weight for medication dosing

Understand the difference between ideal and adjusted body weight, why different dosing weights exist, and why the authorised medicine source must choose the method.

About 8 minRead Guide
BSA medication dosing

Calculation guide

BSA Medication Dosing Explained: mg/m² to the Patient Dose

Understand what an mg/m² medication order means, how BSA turns it into a patient-specific dose in mg, and why volume, rounding and protocol limits are separate steps.

About 12 minRead Guide

Another way to browse

Choose the kind of explanation you need

Clinical area is the main directory. Guide type is a secondary way to understand what each resource is designed to do.

Formula explainers

9

Understand what an equation measures, what its inputs mean and where its limitations begin.

Formula explainers

Calculation guides

11

Work through units, formulas and worked methods before or after using a calculator.

Calculation guides

Comparisons

5

See why similar methods differ and what the current protocol or reference needs you to use.

Formula comparisons

Safety & methodology

6

Check how calculations, rounding, administration and verification decisions should be approached.

Methodology

One topic, connected support

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Calculate

Get the arithmetic now, with the formula and working kept close to the result.

Understand

Use a Guide for context, limitations, comparisons, safety boundaries and worked methods.

Learn and practise

Study one idea at a time, then practise it without losing your place.

Authorship and review

Clear authorship, review timing, and limits of use.

Guide authorGeorge Lambroglou, RNGuide methods, wording and source links are personally reviewed
MedMaths Guides explain calculation methods, formula history and limitations. They support education and arithmetic checking; they do not prescribe, validate or recommend a medicine dose.
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