The pump runs in mL/hr, but the prescription is written as a dose. The concentration connects those two measurements. A concentration of 80 mcg/mL means that every 1 mL of the prepared infusion contains 80 mcg.
If the label gives a direct concentration in mg/mL, convert to mcg/mL using 1 mg = 1000 mcg; the calculator can do this automatically. If the preparation record gives a total amount in mg or mcg, divide the equivalent microgram amount by the verified final volume. Do not assume that the amount of diluent added is always the same as final volume when product-specific preparation instructions state otherwise.
If a bag, syringe or concentration is changed, re-check the calculation using the new current concentration. The same prescribed mcg/kg/min dose can correspond to a different mL/hr pump rate after a concentration change.
If the concentration is not yet stated and you are checking a completed IV preparation from a verified reconstituted vial, transferred solution volume and final total volume, use the Final IV Bag Concentration Calculator first. Then use the verified current concentration here.