Research profile. Donald W. Cockcroft is not affiliated with or endorsed by MedMaths.
Respirology, asthma and airway physiology
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Donald W. Cockcroft, MD, FRCPC, is a Canadian physician and Professor in the Division of Respirology, Critical Care and Sleep Medicine at the University of Saskatchewan. Much of his later research has focused on asthma, airway responsiveness and bronchial challenge testing. In 1976, with M. Henry Gault, he published the study that produced the Cockcroft-Gault equation for estimating creatinine clearance from serum creatinine and patient characteristics.
Formula history
Formula originally described by Donald W. Cockcroft.
Used for: Adults with stable kidney function when Cockcroft-Gault estimated creatinine clearance is the method required by the relevant medicine source; the original derivation studied adult males aged 18 to 92 years
Evidence trail
Cockcroft DW, Gault MH. Cockcroft DW, Gault MH — Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31-41
The PubMed abstract reports derivation from age and 24-hour creatinine excretion/kg in 249 adult male patients aged 18–92 years, with predicted values compared against the mean of two measured 24-hour creatinine clearances in 236 patients; the paper specifies a 15% lower estimate for females.
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Continue with the explanation
These guides explain the calculation, comparison or interpretation questions connected to this research history. This researcher profile provides background on the published work; it is not a calculator or clinical recommendation.
What the Cockcroft-Gault equation calculates, why weight-method selection matters, and when CrCl differs from eGFR.
Open guideUnderstand how CKD-EPI eGFR and Cockcroft-Gault CrCl differ, why their values may not match, and how to follow the estimate and units required by the current source.
Open guideContinue exploring
Known for
Cockcroft-Gault Equation
This source-based research reference profile draws on the original publications above and verified external sources. Donald W. Cockcroft is not affiliated with or endorsed by MedMaths. Unconfirmed fields are left blank rather than estimated.
Reference data verified: 2026-08-14
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