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Laboratory methods

Robert D. Abbott

Research profile. Robert D. Abbott is not affiliated with or endorsed by MedMaths.

Biostatistics and epidemiology

Hillier hyperglycaemia sodium correction (2.4 overall estimate)

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Overview

Robert D. Abbott, PhD, is a biostatistician and epidemiologist who co-authored the 1999 Hillier study evaluating the sodium response to experimentally induced hyperglycaemia. Later peer-reviewed publications list him with the Division of Biostatistics and Epidemiology at the University of Virginia School of Medicine.

Specialty
Biostatistics and epidemiology
Institutions
University of Virginia School of Medicine (published affiliation)

Formula history

Research contributions

Hillier hyperglycaemia sodium correction (2.4 overall estimate)

Based on research published by Robert D. Abbott.

Used for: Alternative empirical estimate of the acute sodium-glucose relationship during experimentally induced hyperglycaemia

Evidence trail

Original research

Hillier TA, Abbott RD, Barrett EJ. Hillier TA, Abbott RD, Barrett EJ — Hyponatremia: evaluating the correction factor for hyperglycemia. American Journal of Medicine. 1999;106(4):399-403

DOI: 10.1016/S0002-9343(99)00055-8View on PubMed (PMID 10225241)Publisher page

Experimental study in six healthy subjects reporting a mean overall sodium change of 2.4 mmol/L per 100 mg/dL glucose change and a non-linear relationship at very high glucose concentrations; 2.4 is presented by MedMaths as the study's overall estimate, not a universal constant.

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Formula co-author

Corrected Sodium Calculator

Adjust serum sodium for hyperglycaemia using the Katz or Hillier correction formula.

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Corrected sodium in hyperglycaemia: what the number means

Why high glucose can lower measured sodium, what a corrected sodium estimate represents, why Katz and Hillier differ, and what the number cannot tell you on its own.

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Researchers connected to this work

TA
Laboratory methods

Teresa A. Hillier

Endocrinology

Known for

Hillier hyperglycaemia sodium correction (2.4 overall estimate)

1 publication 1 linked calculatorProfile
EJ
Laboratory methods

Eugene J. Barrett

Endocrinology and metabolism

Known for

Hillier hyperglycaemia sodium correction (2.4 overall estimate)

1 publication 1 linked calculatorProfile

About this profile

This source-based research reference profile draws on the original publications above and verified external sources. Robert D. Abbott is not affiliated with or endorsed by MedMaths. Unconfirmed fields are left blank rather than estimated.

pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Reference data verified: 2026-08-12

See the methodology and editorial policy for the wider sourcing process.

Profile at a glance

Formulas
1
Publications
1
Verified links
1

Research focus

BiostatisticsEpidemiologyHyperglycaemia and sodium

Source integrity

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