Hillier hyperglycaemia sodium correction (2.4 overall estimate)
Based on research published by Robert D. Abbott.
Used for: Alternative empirical estimate of the acute sodium-glucose relationship during experimentally induced hyperglycaemia
Research profile. Robert D. Abbott is not affiliated with or endorsed by MedMaths.
Biostatistics and epidemiology
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Robert D. Abbott, PhD, is a biostatistician and epidemiologist who co-authored the 1999 Hillier study evaluating the sodium response to experimentally induced hyperglycaemia. Later peer-reviewed publications list him with the Division of Biostatistics and Epidemiology at the University of Virginia School of Medicine.
Formula history
Based on research published by Robert D. Abbott.
Used for: Alternative empirical estimate of the acute sodium-glucose relationship during experimentally induced hyperglycaemia
Evidence trail
Hillier TA, Abbott RD, Barrett EJ. Hillier TA, Abbott RD, Barrett EJ — Hyponatremia: evaluating the correction factor for hyperglycemia. American Journal of Medicine. 1999;106(4):399-403
Experimental study in six healthy subjects reporting a mean overall sodium change of 2.4 mmol/L per 100 mg/dL glucose change and a non-linear relationship at very high glucose concentrations; 2.4 is presented by MedMaths as the study's overall estimate, not a universal constant.
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Hillier hyperglycaemia sodium correction (2.4 overall estimate)
Known for
Hillier hyperglycaemia sodium correction (2.4 overall estimate)
This profile summarizes the published work and draws on the original publications above and verified external sources. It isn't a calculator or clinical advice. Robert D. Abbott isn't affiliated with MedMaths and hasn't endorsed it. Anything we couldn't confirm is left blank, not estimated.
Reference data verified: 2026-08-12
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