Hillier hyperglycaemia sodium correction (2.4 overall estimate)
Based on research published by Teresa A. Hillier.
Used for: Alternative empirical estimate of the acute sodium-glucose relationship during experimentally induced hyperglycaemia
TA
Laboratory methods
Teresa A. Hillier
Historical research profile. Teresa A. Hillier is not affiliated with or endorsed by MedMaths.
Endocrinology
Hillier hyperglycaemia sodium correction (2.4 overall estimate)
Verified MedMaths relationship
Open Corrected Sodium Calculator
We checked this link against the research record.
Overview
Teresa A. Hillier, MD, MS, was an endocrinologist and distinguished investigator whose research included diabetes, gestational diabetes, metabolic disease and osteoporosis. She was lead author of the 1999 American Journal of Medicine experiment that re-evaluated the sodium correction factor during acute hyperglycaemia and reported 2.4 mmol/L per 100 mg/dL as the better overall estimate in that study.
- Qualifications
- MS
- Specialty
- Endocrinology
- Institutions
- Kaiser Permanente Center for Health Research
Formula history
Research contributions
Evidence trail
Original research
Hillier TA, Abbott RD, Barrett EJ. Hillier TA, Abbott RD, Barrett EJ — Hyponatremia: evaluating the correction factor for hyperglycemia. American Journal of Medicine. 1999;106(4):399-403
Experimental study in six healthy subjects reporting a mean overall sodium change of 2.4 mmol/L per 100 mg/dL glucose change and a non-linear relationship at very high glucose concentrations; 2.4 is presented by MedMaths as the study's overall estimate, not a universal constant.
Verified MedMaths links
Verified calculator relationships
Each link below has a recorded relationship type. It may represent formula authorship, co-authorship, historical foundation or interpretation research; none implies endorsement or involvement from Teresa A. Hillier.
Continue with the explanation
Related MedMaths guides
These guides cover the calculation questions connected to this research.
Continue exploring
Researchers connected to this work
RD
Known for
Hillier hyperglycaemia sodium correction (2.4 overall estimate)
1 publication 1 linked calculatorProfile
EJ
Known for
Hillier hyperglycaemia sodium correction (2.4 overall estimate)
1 publication 1 linked calculatorProfile
About this profile
This profile summarizes the published work and draws on the original publications above and verified external sources. It isn't a calculator or clinical advice. Teresa A. Hillier isn't affiliated with MedMaths and hasn't endorsed it. Anything we couldn't confirm is left blank, not estimated.
Reference data verified: 2026-08-12
See the methodology and editorial policy for the wider sourcing process.