Hillier hyperglycaemia sodium correction (2.4 overall estimate)
Based on research published by Teresa A. Hillier.
Used for: Alternative empirical estimate of the acute sodium-glucose relationship during experimentally induced hyperglycaemia
TA
Laboratory methods
Teresa A. Hillier
Historical research profile. Teresa A. Hillier is not affiliated with or endorsed by MedMaths.
Endocrinology
Hillier hyperglycaemia sodium correction (2.4 overall estimate)
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Overview
Teresa A. Hillier, MD, MS, was an endocrinologist and distinguished investigator whose research included diabetes, gestational diabetes, metabolic disease and osteoporosis. She was lead author of the 1999 American Journal of Medicine experiment that re-evaluated the sodium correction factor during acute hyperglycaemia and reported 2.4 mmol/L per 100 mg/dL as the better overall estimate in that study.
- Qualifications
- MS
- Specialty
- Endocrinology
- Institutions
- Kaiser Permanente Center for Health Research
Formula history
Research contributions
Evidence trail
Original research
Hillier TA, Abbott RD, Barrett EJ. Hillier TA, Abbott RD, Barrett EJ — Hyponatremia: evaluating the correction factor for hyperglycemia. American Journal of Medicine. 1999;106(4):399-403
Experimental study in six healthy subjects reporting a mean overall sodium change of 2.4 mmol/L per 100 mg/dL glucose change and a non-linear relationship at very high glucose concentrations; 2.4 is presented by MedMaths as the study's overall estimate, not a universal constant.
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RD
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Hillier hyperglycaemia sodium correction (2.4 overall estimate)
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EJ
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Hillier hyperglycaemia sodium correction (2.4 overall estimate)
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About this profile
This source-based research reference profile draws on the original publications above and verified external sources. Teresa A. Hillier is not affiliated with or endorsed by MedMaths. Unconfirmed fields are left blank rather than estimated.
Reference data verified: 2026-08-12
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